Missouri Nurse Practitioner Licensure Steps - 2022

AKA: CRNP License, APRN Licensure

Last Reviewed: October 1st, 2022

Nurse Practitioner Licensure Requirements in Missouri

Follow below to learn how to become a nurse practitioner (NP) in Missouri.

Initial Registered Nurse (RN) Licensure

Already have your RN License?Skip to the next section

If you do not hold a single-state registered nurse (RN) license to practice in Missouri or a multi-state RN license from one of the NLC member states, you must apply for an RN license from the Missouri Board of Nursing.

Holders of multi-state RN licenses from NLC states are only required to apply for a license in Missouri when they choose to change their primary state of residence to Missouri. You can apply for an RN license by Examination or by Endorsement.

RN by Examination

This is the ideal application route for people who have never been licensed to practice as RNs in any state in the US.

  • Applicants using this route should hold at least an associate’s degree in nursing to qualify for RN licensure. However, a bachelor’s degree is preferable if you intend to make the switch to an NP role in the near future. Recent nursing school graduates are allowed to practice with supervision for up to 90 days immediately after their graduation or until they pass the entry-level nursing test (whichever comes first).
  • Proof of your academic qualification is required. You must request that an original copy of your transcript be sent to the board by your awarding institution. These documents should be sent to the following address:

    Missouri State Board of Nursing

    P.O. Box 656

    Jefferson City, MO. 65102-0656
  • International students are required to have their credentials evaluated by the CGFNS or Josef Silny & Associates for equivalence with that of nurses trained in Missouri. As an additional requirement, foreign students will be required to pass English proficiency tests. An overall passing score of 6.5 with 7 in the speaking segment of the academic module of the IELTS paper test, 725 in the listening and reading modules of the TOEIC, a passing score of 540 in the paper TOEFL test, or passing score of 83 and speaking score of 26 for the internet option are acceptable. They are also required to complete the verification of their qualifications, identity, license, and residency on the Trueprofile platform. You can find the application credentials required for foreign-trained applicants on page 4 here.  All original documents provided by foreign-trained nurses must come with an English translation unless they were originally presented in English. All applicants are required to submit proof of lawful presence in the US such as a valid visa, US passport, US birth certificate, permanent resident card, 1-94, 1-20, and other acceptable documents.
  • All applicants are required to submit a correctly filled form and pass the National Council Licensure Examination for Registered Nurses (NCLEX-RN). You are to register for the examination here for a fee of $200. The best time to register for the NCLEX-RN is between 1-3 months before your date of graduation from your basic nursing program. You are to complete your licensure application before applying for the test so that the board can notify the testing service of your eligibility. After this is done, you will receive an Authorization to Test (ATT). Hence, you must keep your name and contact information, particularly your email address consistent all through the application process.
  • Download and complete you application for RN license here.

Note that there is no application fee for first-time applicants via examination and all supporting documents are to be sent via mail.

RN by Endorsement

Nurses who have been licensed to practice as RNs in the past in any state or territory in the US are to apply via this route provided that they have passed the NCLEX-RN and fulfilled all other requirements for being issued an initial license in the said state.

  • Enroll in the Nursys E-Notify as a Nurse.
  • If you qualify for a temporary license, you will receive it through this platform.
  • When enrolling, you can opt-in for automatic reminders for your license renewal. RN licenses expire by April 30th of every odd-numbered year.
  • The application is completed on paper for a non-refundable fee of $105 which should be sent by money order or check payable to the Missouri State Board of Nursing by mail:

    Missouri State Board of Nursing

    P.O. Box 656

    Jefferson City, MO. 65102-0656
  • Request an original copy of your transcript be sent by the awarding institution to the board. This transcript must contain your date of graduation from the program and the degree you were awarded.
  • Another compulsory step is the verification of licensure from the state where you hold a valid RN license. This is done with the Nursys Licensure Verification for Endorsement function. If your board does not report to Nursys, you must contact them concerning their verification process.
  • You will also be required to provide proof of lawful presence in the US. Internationally-trained applicants are required to submit English Proficiency tests results as were also covered in the previous section.

All applicants are required to participate in a fingerprint-based criminal background check exercise by registering here with the 4-digit registration number 0001. Following your registration, simply follow the prompts on the website.

Ensure that your name, social security number, and contact details match those used in your licensure application. You will be required to redo the process if there is any discrepancy. If you are outside Missouri, follow these steps for your fingerprinting. Note that the fingerprinting and background check require a fee as decided by the vendor. Nurses licensed in California with the 30-unit option are not qualified for a license in Missouri.

Advanced Education Requirement

The Missouri Nurse Practice Act requires anyone who will be licensed to serve in the role of a nurse practitioner or any other APRN to have advanced education leading to the award of a graduate degree (master’s or higher).

The program must be taken at an institution that is regionally accredited by the Council for Higher Education Accreditation (CHEA). The program must also have been accredited by appropriate national certifying bodies. Graduate programs must equip participants with knowledge and skills to practice as nurse practitioners serving specific population foci. Here you can find all schools offering nurse practitioner programs in Missouri.

Your coursework must include advanced pathophysiology, pharmacology, and clinical management among others. You must also have completed at least 1500 hours of clinical practice in your specialty. As all holders of an APRN license possess prescriptive authority for non-controlled substances, nurse practitioners who will be required to handle controlled substances must apply for a permit. Academic requirements for applying include proof of one of the following

  • A letter from your APRN program showing in detail how preceptorship was integrated into your program
  • 45 CE units of pharmacology or 3 hours of advanced pharmacology within the immediate past five years
  • 1000 hours of clinical APRN practice
  • 300 hours of APRN preceptorship in prescribing medications and therapeutic devices

National Certification

The task of determining the quality of your advanced practice education is left to appropriate national certifying agencies recognized by the board. These agencies grant certification to professionals in specific specialty areas and for certain population foci based on successfully passing examination.

The Missouri board of nursing has created a list of recognized agencies for the certification of NPs which include:

  • National Certification Corporation (NCC)
  • Pediatric Nursing Certification Board (PNCB)
  • American Academy of Nurse Practitioners (AANP)
  • American Nurses Credentialing Center (ANCC)
  • American Association of Critical-Care Nurses (AACN)

Getting Licensed to Practice as a Nurse Practitioner in Missouri

Before applying for an APRN license in Missouri, you must familiarize yourself with the Nurse Practice Act. The first step is to register on the Nursys E-Notify platform through which you will receive your license. You should also opt for the automatic license renewal reminder.

The application is via paper and requires a fee of $150 which should be mailed with other supporting documentation in the form of a money order or check (cashier’s or personal) made payable to the Missouri State Board of Nursing.

Applicants for an APRN license are also required to submit proof of their national certification which may be a copy of your certification card or a statement to the effect from the relevant national certifying agency. This proof must reflect the date of expiry of the certification.

Finally, you are required to complete an Authorization to Release Confidential Information and submit it with the other documents.

The APRN license comes with prescriptive authority for non-controlled medication. If your role required that you prescribe or dispense controlled drugs, you must apply for a certificate of controlled drug prescriptive authority according to 335.019, RSMo. You can find the application instructions here.